Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear pr...
Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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We examined cell cycle–dependent changes in the proteome of human cells by systematically measuring protein dynamics in individual living cells. We used time-lapse microscopy to measure the dynamics of a random subset of 20 nuclear proteins, each tagged with yellow fluorescent protein (YFP) at its endogenous chromosomal location. We synchronized th...
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Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins
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TN_cdi_proquest_miscellaneous_68108249
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68108249
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth892
