Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface
Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
Sustained exposure to pathological stress stimulates the heart to hypertrophy, increasing disease and mortality risk. New therapies to blunt this process include targeting enzymes below the cell membrane that serve as strategic nodes for hypertrophy regulation.
Rho kinase (ROCK) is activated in cardiac hypertrophy and stimulates fi...
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Full title
Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface
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TN_cdi_proquest_miscellaneous_68108386
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68108386
Other Identifiers
ISSN
1474-1776,1474-1784
E-ISSN
1474-1784
DOI
10.1038/nrd2193
