Inactivation of the p53 pathway in retinoblastoma
Inactivation of the p53 pathway in retinoblastoma
About this item
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Author / Creator
LAURIE, Nikia A , DONOVAN, Stacy L , JOHNSON, Dianna , WILSON, Matthew , RODRIGUEZ-GALINDO, Carlos , QUARTO, Micaela , FRANCOZ, Sarah , MENDRYSA, Susan M , KIPLIN GUY, R , MARINE, Jean-Christophe , JOCHEMSEN, Aart G , DYER, Michael A , SHIH, Chie-Schin , JIAKUN ZHANG , MILLS, Nicholas , FULLER, Christine , TEUNISSE, Amina , LAM, Suzanne , RAMOS, Yolande and MOHAN, Adithi
Publisher
London: Nature Publishing
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing
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Scope and Contents
Contents
Most human tumours have genetic mutations in their Rb and p53 pathways, but retinoblastoma is thought to be an exception. Studies suggest that retinoblastomas, which initiate with mutations in the gene retinoblastoma 1 (RB1), bypass the p53 pathway because they arise from intrinsically death-resistant cells during retinal development. In contrast t...
Alternative Titles
Full title
Inactivation of the p53 pathway in retinoblastoma
Authors, Artists and Contributors
Author / Creator
DONOVAN, Stacy L
JOHNSON, Dianna
WILSON, Matthew
RODRIGUEZ-GALINDO, Carlos
QUARTO, Micaela
FRANCOZ, Sarah
MENDRYSA, Susan M
KIPLIN GUY, R
MARINE, Jean-Christophe
JOCHEMSEN, Aart G
DYER, Michael A
SHIH, Chie-Schin
JIAKUN ZHANG
MILLS, Nicholas
FULLER, Christine
TEUNISSE, Amina
LAM, Suzanne
RAMOS, Yolande
MOHAN, Adithi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68112584
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68112584
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature05194
