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The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand...

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68122855

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

About this item

Full title

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

Publisher

United States

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (45), p.16900-16905

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

GPIbalpha binding to von Willebrand factor (VWF) exposed at a site of vascular injury is thought to be the first step in the formation of a hemostatic plug. However, our previous studies in VWF-deficient mice demonstrated delayed but not absent arterial thrombus formation, suggesting that, under these conditions, GPIbalpha may bind other ligands or...

Alternative Titles

Full title

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68122855

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68122855

Other Identifiers

ISSN

0027-8424

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