Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism
Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
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More information
Scope and Contents
Contents
Using fluorescence resonance energy transfer to monitor distances within single molecules of abortively initiating transcription initiation complexes, we show that initial transcription proceeds through a "scrunching" mechanism, in which RNA polymerase (RNAP) remains fixed on promoter DNA and pulls downstream DNA into itself and past its active cen...
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Full title
Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism
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Record Identifier
TN_cdi_proquest_miscellaneous_68159401
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68159401
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1131399
