Histone deacetylase inhibitors: molecular mechanisms of action
Histone deacetylase inhibitors: molecular mechanisms of action
About this item
Full title
Author / Creator
Xu, W S , Parmigiani, R B and Marks, P A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
This review focuses on the mechanisms of action of histone deacetylase (HDAC) inhibitors (HDACi), a group of recently discovered ‘targeted’ anticancer agents. There are 18 HDACs, which are generally divided into four classes, based on sequence homology to yeast counterparts. Classical HDACi such as the hydroxamic acid-based vorinostat (also known a...
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Full title
Histone deacetylase inhibitors: molecular mechanisms of action
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_68159569
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68159569
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1210620
