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Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis

Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68174049

Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis

About this item

Full title

Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis

Publisher

London: Nature Publishing Group UK

Journal title

Gene therapy, 2006-12, Vol.13 (23), p.1645-1656

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human immunodeficiency virus-1 (HIV-1) infection in the central nervous system (CNS) may lead to neuronal loss and progressively deteriorating CNS function: HIV-1 gene products, especially gp120, induce free radical-mediated apoptosis. Reactive oxygen species (ROS), are among the potential mediators of these effects. Neurons readily form ROS after...

Alternative Titles

Full title

Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68174049

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68174049

Other Identifiers

ISSN

0969-7128

E-ISSN

1476-5462

DOI

10.1038/sj.gt.3302821

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