Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis
Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Human immunodeficiency virus-1 (HIV-1) infection in the central nervous system (CNS) may lead to neuronal loss and progressively deteriorating CNS function: HIV-1 gene products, especially gp120, induce free radical-mediated apoptosis. Reactive oxygen species (ROS), are among the potential mediators of these effects. Neurons readily form ROS after...
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Full title
Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis
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TN_cdi_proquest_miscellaneous_68174049
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68174049
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ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/sj.gt.3302821