Ras transformation requires metabolic control by 6-phosphofructo-2-kinase
Ras transformation requires metabolic control by 6-phosphofructo-2-kinase
About this item
Full title
Author / Creator
Telang, S , Yalcin, A , Clem, A L , Bucala, R , Lane, A N , Eaton, J W and Chesney, J
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neoplastic cells transport large amounts of glucose in order to produce anabolic precursors and energy within the inhospitable environment of a tumor. The
ras
signaling pathway is activated in several cancers and has been found to stimulate glycolytic flux to lactate. Glycolysis is regulated by
ras
via the activity of 6-phosphofructo-2-...
Alternative Titles
Full title
Ras transformation requires metabolic control by 6-phosphofructo-2-kinase
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68179223
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68179223
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1209709
