Perforin-mediated target-cell death and immune homeostasis
Perforin-mediated target-cell death and immune homeostasis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells kill virus-infected and transformed cells through both the death-receptor and granule exocytosis pathways. The perforin-dependent granule exocytosis mechanism is crucial for protecting the host against many viral infections, and in mice this pathway is involved in immune sur...
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Full title
Perforin-mediated target-cell death and immune homeostasis
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TN_cdi_proquest_miscellaneous_68185306
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68185306
Other Identifiers
ISSN
1474-1733
E-ISSN
1474-1741,1365-2567
DOI
10.1038/nri1983
