FcRn: the neonatal Fc receptor comes of age
FcRn: the neonatal Fc receptor comes of age
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
The neonatal Fc receptor for IgG (FcRn) is responsible for the transfer of passive humoral immunity from the mother to the newborn in rodents and humans. Throughout life, FcRn contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation.
FcRn is expressed in various tissues in adults. Th...
Alternative Titles
Full title
FcRn: the neonatal Fc receptor comes of age
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Record Identifier
TN_cdi_proquest_miscellaneous_68194563
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68194563
Other Identifiers
ISSN
1474-1733
E-ISSN
1474-1741,1365-2567
DOI
10.1038/nri2155
