Repression of p53 activity by Smyd2-mediated methylation
Repression of p53 activity by Smyd2-mediated methylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Specific sites of lysine methylation on histones correlate with either activation or repression of transcription
1
,
2
,
3
. The tumour suppressor p53 (refs
4–7
) is one of only a few non-histone proteins known to be regulated by lysine methylation
8
. Here we report a lysine methyltransferase, Smyd2, that methylates a...
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Repression of p53 activity by Smyd2-mediated methylation
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TN_cdi_proquest_miscellaneous_68209387
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68209387
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0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature05287