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Repression of p53 activity by Smyd2-mediated methylation

Repression of p53 activity by Smyd2-mediated methylation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68209387

Repression of p53 activity by Smyd2-mediated methylation

About this item

Full title

Repression of p53 activity by Smyd2-mediated methylation

Publisher

London: Nature Publishing Group UK

Journal title

Nature, 2006-11, Vol.444 (7119), p.629-632

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Specific sites of lysine methylation on histones correlate with either activation or repression of transcription
1
,
2
,
3
. The tumour suppressor p53 (refs
4–7
) is one of only a few non-histone proteins known to be regulated by lysine methylation
8
. Here we report a lysine methyltransferase, Smyd2, that methylates a...

Alternative Titles

Full title

Repression of p53 activity by Smyd2-mediated methylation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68209387

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68209387

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687,1476-4679

DOI

10.1038/nature05287

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