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A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inh...

A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inh...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68216134

A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inhibits tumor xenografts

About this item

Full title

A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inhibits tumor xenografts

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The journal of gene medicine, 2006-12, Vol.8 (12), p.1407-1415

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Background
In this study we investigated whether a particular branched HK polymer, H2K4b, was an effective in vivo carrier of plasmids expressing the antiangiogenic kringle 1–5 or the tumor suppressor p53.
Methods
H2K4b was synthesized on a solid‐phase peptide synthesizer. Distribution, optimization and time course studies were done in tum...

Alternative Titles

Full title

A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inhibits tumor xenografts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68216134

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68216134

Other Identifiers

ISSN

1099-498X

E-ISSN

1521-2254

DOI

10.1002/jgm.982

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