New Aminocoumarin Antibiotics Derived from 4-Hydroxycinnamic Acid are Formed after Heterologous Expr...
New Aminocoumarin Antibiotics Derived from 4-Hydroxycinnamic Acid are Formed after Heterologous Expression of a Modified Clorobiocin Biosynthetic Gene Cluster
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Three new aminocoumarin antibiotics, termed ferulobiocin, 3-chlorocoumarobiocin and 8′-dechloro-3-chlorocoumarobiocin, were isolated from the culture broth of a
Streptomyces coelicolor
M512 strain expressing a modified clorobiocin biosynthetic gene cluster. Structural analysis showed that these new aminocoumarins were very similar to clorobio...
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New Aminocoumarin Antibiotics Derived from 4-Hydroxycinnamic Acid are Formed after Heterologous Expression of a Modified Clorobiocin Biosynthetic Gene Cluster
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TN_cdi_proquest_miscellaneous_68249572
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68249572
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ISSN
0021-8820
E-ISSN
1881-1469
DOI
10.1038/ja.2007.64