Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice
Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice
About this item
Full title
Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice
Author / Creator
Publisher
Germany
Journal title
Psychopharmacology, 2007-10, Vol.194 (3), p.361-369
Language
English
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Publication information
Publisher
Germany
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Scope and Contents
Contents
Gamma-amino-butyric acid (GABA)(B) receptors play a key role in the pathophysiology of psychotic disorders. We previously reported that baclofen, the prototypical GABA(B) agonist, elicits antipsychotic-like effects in the rat paradigm of prepulse inhibition (PPI) of the startle, a highly validated animal model of schizophrenia.
We studied the ro...
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Full title
Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice
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Record Identifier
TN_cdi_proquest_miscellaneous_68262593
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68262593
Other Identifiers
ISSN
0033-3158
DOI
10.1007/s00213-007-0845-5
