Dynamic Visualization of Thrombopoiesis Within Bone Marrow
Dynamic Visualization of Thrombopoiesis Within Bone Marrow
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Platelets are generated from megakaryocytes (MKs) in mammalian bone marrow (BM) by mechanisms that remain poorly understood. Here we describe the use of multiphoton intravital microscopy in intact BM to visualize platelet generation in mice. MKs were observed as sessile cells that extended dynamic proplatelet-like protrusions into microvessels. The...
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Full title
Dynamic Visualization of Thrombopoiesis Within Bone Marrow
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Record Identifier
TN_cdi_proquest_miscellaneous_68300721
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68300721
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1146304
