Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Key Points
A wide variety of tumours and their precursor lesions undergo exacerbated
de novo
biogenesis of fatty acids (FAs) irrespective of the levels of circulating lipids. Neoplastic lipogenesis is reflected by significantly increased activity and coordinate expression of several lipogenic enzymes in tumour cells. Upregulation of fatty...
Alternative Titles
Full title
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
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TN_cdi_proquest_miscellaneous_68308522
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68308522
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc2222
