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Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively in...

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68327283

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/“triple-negative” breast cancer cell lines growing in vitro

About this item

Full title

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/“triple-negative” breast cancer cell lines growing in vitro

Publisher

Dordrecht: Springer

Journal title

Breast cancer research and treatment, 2007-11, Vol.105 (3), p.319-326

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer

More information

Scope and Contents

Contents

Dasatinib is an orally active small molecule kinase inhibitor of both the src and abl proteins. To evaluate the potential role of dasatinib in breast cancer we used 39 human breast cancer cell lines that have been molecular profiled using Agilent Microarrays. They represent both luminal and basal breast cancer subtypes based on the relative gene ex...

Alternative Titles

Full title

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/“triple-negative” breast cancer cell lines growing in vitro

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68327283

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68327283

Other Identifiers

ISSN

0167-6806

E-ISSN

1573-7217

DOI

10.1007/s10549-006-9463-x

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