STAT3 Mutations in the Hyper-IgE Syndrome
STAT3 Mutations in the Hyper-IgE Syndrome
About this item
Full title
Author / Creator
Holland, Steven M , DeLeo, Frank R , Elloumi, Houda Z , Hsu, Amy P , Uzel, Gulbu , Brodsky, Nina , Freeman, Alexandra F , Demidowich, Andrew , Davis, Joie , Turner, Maria L , Anderson, Victoria L , Darnell, Dirk N , Welch, Pamela A , Kuhns, Douglas B , Frucht, David M , Malech, Harry L , Gallin, John I , Kobayashi, Scott D , Whitney, Adeline R , Voyich, Jovanka M , Musser, James M , Woellner, Cristina , Schäffer, Alejandro A , Puck, Jennifer M and Grimbacher, Bodo
Publisher
Boston, MA: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Boston, MA: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Identifying the gene that underlies the hyper-IgE immune syndrome — also known as Job's syndrome — has been a challenge. Affected persons typically have extremely high levels of IgE and are susceptible to cold staphylococcal abscesses, pneumonia, and eczema. The cause of this disease is now established: mutations in
STAT3.
Identifying the gen...
Alternative Titles
Full title
STAT3 Mutations in the Hyper-IgE Syndrome
Authors, Artists and Contributors
Author / Creator
DeLeo, Frank R
Elloumi, Houda Z
Hsu, Amy P
Uzel, Gulbu
Brodsky, Nina
Freeman, Alexandra F
Demidowich, Andrew
Davis, Joie
Turner, Maria L
Anderson, Victoria L
Darnell, Dirk N
Welch, Pamela A
Kuhns, Douglas B
Frucht, David M
Malech, Harry L
Gallin, John I
Kobayashi, Scott D
Whitney, Adeline R
Voyich, Jovanka M
Musser, James M
Woellner, Cristina
Schäffer, Alejandro A
Puck, Jennifer M
Grimbacher, Bodo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68410592
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68410592
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa073687
