Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines...
Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction
About this item
Full title
Author / Creator
Kaufmann, Daniel E , Kavanagh, Daniel G , Pereyra, Florencia , Zaunders, John J , Mackey, Elizabeth W , Miura, Toshiyuki , Palmer, Sarah , Brockman, Mark , Rathod, Almas , Piechocka-Trocha, Alicja , Baker, Brett , Zhu, Baogong , Le Gall, Sylvie , Waring, Michael T , Ahern, Ryan , Moss, Kristin , Kelleher, Anthony D , Coffin, John M , Freeman, Gordon J , Rosenberg, Eric S and Walker, Bruce D
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
In progressive viral infection, antiviral T cell function is impaired by poorly understood mechanisms. Here we report that the inhibitory immunoregulatory receptor CTLA-4 was selectively upregulated in human immunodeficiency virus (HIV)–specific CD4
+
T cells but not CD8
+
T cells in all categories of HIV-infected subjects evaluated, wi...
Alternative Titles
Full title
Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction
Authors, Artists and Contributors
Author / Creator
Kavanagh, Daniel G
Pereyra, Florencia
Zaunders, John J
Mackey, Elizabeth W
Miura, Toshiyuki
Palmer, Sarah
Brockman, Mark
Rathod, Almas
Piechocka-Trocha, Alicja
Baker, Brett
Zhu, Baogong
Le Gall, Sylvie
Waring, Michael T
Ahern, Ryan
Moss, Kristin
Kelleher, Anthony D
Coffin, John M
Freeman, Gordon J
Rosenberg, Eric S
Walker, Bruce D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68415754
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68415754
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni1515
