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Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin

Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68424145

Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin

About this item

Full title

Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin

Publisher

India

Journal title

Journal of biosciences, 2007-09, Vol.32 (6), p.1133-1138

Language

English

Formats

Publication information

Publisher

India

More information

Scope and Contents

Contents

Beta-catenin is the key transducer of Wingless-type MMTV integration site family member (Wnt) signalling, upregulation of which is the cause of cancer of the colon and other tissues. In the absence of Wnt signals, beta-catenin is targeted to ubiquitin-proteasome-mediated degradation. Here we present the functional characterization of E3-ubiquitin l...

Alternative Titles

Full title

Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68424145

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68424145

Other Identifiers

ISSN

0250-5991

E-ISSN

0973-7138

DOI

10.1007/s12038-007-0114-0

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