Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of h...
Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study
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Author / Creator
Krüger, Stefan , Silber, Ann-Sophie , Engel, Christoph , Görgens, Heike , Mangold, Elisabeth , Pagenstecher, Constanze , Holinski-Feder, Elke , von Knebel Doeberitz, Magnus , Moeslein, Gabriela , Dietmaier, Wolfgang , Stemmler, Susanne , Friedl, Waltraut , Rüschoff, Josef , Schackert, Hans K , for the German Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Consortium and German Hereditary Non-Polyposis Colorectal Cancer Consortium
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
Subjects
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Scope and Contents
Contents
RNASEL is thought to be a susceptibility gene for hereditary prostate cancer and encodes the endoribonuclease RNase L, which has a role in apoptosis and is a candidate tumour-suppressor protein. A common sequence variation in
RNASEL, Arg462Gln, has been associated with hereditary and sporadic prostate cancer, and the Gln variant has about three-...
Alternative Titles
Full title
Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study
Authors, Artists and Contributors
Author / Creator
Silber, Ann-Sophie
Engel, Christoph
Görgens, Heike
Mangold, Elisabeth
Pagenstecher, Constanze
Holinski-Feder, Elke
von Knebel Doeberitz, Magnus
Moeslein, Gabriela
Dietmaier, Wolfgang
Stemmler, Susanne
Friedl, Waltraut
Rüschoff, Josef
Schackert, Hans K
for the German Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Consortium
German Hereditary Non-Polyposis Colorectal Cancer Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68430218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68430218
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(05)70253-9