The yin and yang of neurotrophin action
The yin and yang of neurotrophin action
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Mature neurotrophins bind preferentially to Trk receptor tyrosine kinases. By contrast, proneurotrophins (neurotrophin precursors) bind with high affinity to the p75 neurotrophin receptor (p75
NTR
).
Interaction of mature neurotrophins with Trk receptors leads to cell survival, whereas binding of pro-nerve growth factor (proN...
Alternative Titles
Full title
The yin and yang of neurotrophin action
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TN_cdi_proquest_miscellaneous_68436705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68436705
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ISSN
1471-003X
E-ISSN
1471-0048,1469-3178
DOI
10.1038/nrn1726
