Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Glycogen synthesis is normally absent in neurons. However, inclusion bodies resembling abnormal glycogen accumulate in several neurological diseases, particularly in progressive myoclonus epilepsy or Lafora disease. We show here that mouse neurons have the enzymatic machinery for synthesizing glycogen, but that it is suppressed by retention of musc...
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Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy
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TN_cdi_proquest_miscellaneous_68445846
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68445846
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1998
