Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The transcription factor NF-κB is a key regulator of cellular activation, proliferation and apoptosis. Defects in the NF-κB pathway contribute to a broad array of malignant, neurodegenerative and chronic inflammatory diseases. IKK-dependent IκBα degradation by the 26S proteasome is a critical NF-κB regulatory control point, which is emerging as an...
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Full title
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
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TN_cdi_proquest_miscellaneous_68472053
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68472053
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth779
