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IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth musc...

IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth musc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68473298

IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts

About this item

Full title

IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts

Publisher

Berlin: Berlin/Heidelberg : Springer-Verlag

Journal title

Diabetologia, 2007-12, Vol.50 (12), p.2534-2543

Language

English

Formats

Publication information

Publisher

Berlin: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

Aims/hypothesis Mitogenic activity of insulin and insulin analogues and the involvement of the IGF-1 receptor (IGF-1R) is still a controversial issue. We compared levels of the proteins IGF-1R and insulin receptor (InsR) in fibroblasts and smooth muscle cells from healthy donors and assessed the downstream signalling and growth-promoting activity o...

Alternative Titles

Full title

IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68473298

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68473298

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-007-0815-9

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