PIN-1 promoter polymorphisms in mild cognitive impairment and susceptibility to Alzheimer’s disease:...
PIN-1 promoter polymorphisms in mild cognitive impairment and susceptibility to Alzheimer’s disease: a preliminary report
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Germany: Springer Nature B.V
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Language
English
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Germany: Springer Nature B.V
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Peptydil prolyl cis-trans isomerase (PIN-1), which specifically regulates the conformational changes following phosphorylation of several proteins, targets the inactive hyper-phosphorylated tau on the Thr231-Pro motif and directly restores its biological function. Interestingly, PIN-1 is oxidatively inhibited not only in Alzheimer's disease brain b...
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PIN-1 promoter polymorphisms in mild cognitive impairment and susceptibility to Alzheimer’s disease: a preliminary report
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TN_cdi_proquest_miscellaneous_68505575
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68505575
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ISSN
1594-0667
E-ISSN
1720-8319
DOI
10.1007/BF03324722
