Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
About this item
Full title
Author / Creator
Gordon, Paul H, MD , Moore, Dan H, PhD , Miller, Robert G, MD , Florence, Julaine M, DPT , Verheijde, Joseph L, PhD , Doorish, Carolyn, BA , Hilton, Joan F, ScD , Spitalny, G Mark, MA , MacArthur, Robert B, PhD , Mitsumoto, Hiroshi, MD , Neville, Hans E, MD , Boylan, Kevin, MD , Mozaffar, Tahseen, MD , Belsh, Jerry M, MD , Ravits, John, MD , Bedlack, Richard S, MD , Graves, Michael C, MD , McCluskey, Leo F, MD , Barohn, Richard J, MD , Tandan, Rup, MD , for the Western ALS Study Group and Western ALS Study Group
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Minocycline has anti-apoptotic and anti-inflammatory effects in vitro, and extends survival in mouse models of some neurological conditions. Several trials are planned or are in progress to assess whether minocycline slows human neurodegeneration. We aimed to test the efficacy of minocycline as a treatment for amyotrophic lateral...
Alternative Titles
Full title
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
Authors, Artists and Contributors
Author / Creator
Moore, Dan H, PhD
Miller, Robert G, MD
Florence, Julaine M, DPT
Verheijde, Joseph L, PhD
Doorish, Carolyn, BA
Hilton, Joan F, ScD
Spitalny, G Mark, MA
MacArthur, Robert B, PhD
Mitsumoto, Hiroshi, MD
Neville, Hans E, MD
Boylan, Kevin, MD
Mozaffar, Tahseen, MD
Belsh, Jerry M, MD
Ravits, John, MD
Bedlack, Richard S, MD
Graves, Michael C, MD
McCluskey, Leo F, MD
Barohn, Richard J, MD
Tandan, Rup, MD
for the Western ALS Study Group
Western ALS Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68544113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68544113
Other Identifiers
ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(07)70270-3
