A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal h...
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Nitric oxide (NO) production by endothelial cell nitric oxide synthase (eNOS) in sinusoidal endothelial cells is reduced in the injured liver and leads to intrahepatic portal hypertension. We sought to understand the mechanism underlying defective eNOS function. Phosphorylation of the serine-threonine kinase Akt, which activates eNOS, was substanti...
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Full title
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
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TN_cdi_proquest_miscellaneous_68560029
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68560029
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1289
