The targeted disruption of the MYPT1 gene results in embryonic lethality
The targeted disruption of the MYPT1 gene results in embryonic lethality
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Publisher
Dordrecht: Springer
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Language
English
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Publisher
Dordrecht: Springer
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Contents
Myosin phosphatase (MP) is a major phosphatase responsible for the dephosphorylation of the regulatory light chain of myosin II. MYPT1, a target subunit of smooth and nonmuscle MP, is responsible for activation and regulation of MP. To identity the physiological roles of MP, we have generated MYPT1-deficient mice by gene targeting. The heterozygous...
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Full title
The targeted disruption of the MYPT1 gene results in embryonic lethality
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TN_cdi_proquest_miscellaneous_68561819
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68561819
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ISSN
0962-8819
E-ISSN
1573-9368
DOI
10.1007/s11248-005-3453-3
