Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome
Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
We describe a DNA sequencing technology in which a commonly available, inexpensive epifluorescence microscope is converted to rapid nonelectrophoretic DNA sequencing automation. We apply this technology to resequence an evolved strain of Escherichia coli at less than one error per million consensus bases. A cell-free, mate-paired library provided s...
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Full title
Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome
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TN_cdi_proquest_miscellaneous_68569866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68569866
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1117389