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Functional inhibition of NF-kappaB signal transduction in alphavbeta3 integrin expressing endothelia...

Functional inhibition of NF-kappaB signal transduction in alphavbeta3 integrin expressing endothelia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68579923

Functional inhibition of NF-kappaB signal transduction in alphavbeta3 integrin expressing endothelial cells by using RGD-PEG-modified adenovirus with a mutant IkappaB gene

About this item

Full title

Functional inhibition of NF-kappaB signal transduction in alphavbeta3 integrin expressing endothelial cells by using RGD-PEG-modified adenovirus with a mutant IkappaB gene

Publisher

England: National Library of Medicine - MEDLINE Abstracts

Journal title

Arthritis research & therapy, 2006, Vol.8 (1), p.R32-R32

Language

English

Formats

Publication information

Publisher

England: National Library of Medicine - MEDLINE Abstracts

More information

Scope and Contents

Contents

In order to selectively block nuclear factor kappaB (NF-kappaB)-dependent signal transduction in angiogenic endothelial cells, we constructed an alphavbeta3 integrin specific adenovirus encoding dominant negative IkappaB (dnIkappaB) as a therapeutic gene. By virtue of RGD modification of the PEGylated virus, the specificity of the cell entry pathwa...

Alternative Titles

Full title

Functional inhibition of NF-kappaB signal transduction in alphavbeta3 integrin expressing endothelial cells by using RGD-PEG-modified adenovirus with a mutant IkappaB gene

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68579923

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68579923

Other Identifiers

ISSN

1478-6354

E-ISSN

1478-6362

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