An Expression Signature for p53 Status in Human Breast Cancer Predicts Mutation Status, Transcriptio...
An Expression Signature for p53 Status in Human Breast Cancer Predicts Mutation Status, Transcriptional Effects, and Patient Survival
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Perturbations of the p53 pathway are associated with more aggressive and therapeutically refractory tumors. However, molecular assessment of p53 status, by using sequence analysis and immunohistochemistry, are incomplete assessors of p53 functional effects. We posited that the transcriptional fingerprint is a more definitive downstream indicator of...
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An Expression Signature for p53 Status in Human Breast Cancer Predicts Mutation Status, Transcriptional Effects, and Patient Survival
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TN_cdi_proquest_miscellaneous_68606443
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68606443
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0506230102
