Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Protein ubiquitination regulates many cellular processes, including protein degradation, signal transduction, DNA repair and cell division. In the classical model, a uniform polyubiquitin chain that is linked through Lys 48 is required for recognition and degradation by the 26S proteasome. Here, we used a reconstituted system and quantitative mass...
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Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
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TN_cdi_proquest_miscellaneous_68610019
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68610019
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb1436