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Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68664785

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

About this item

Full title

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2005-10, Vol.12 (10), p.847-854

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Telomere end-binding proteins (TEBPs) bind to the guanine-rich overhang (G-overhang) of telomeres. Although the DNA binding properties of TEBPs have been investigated
in vitro
, little is known about their functions
in vivo
. Here we use RNA interference to explore
in vivo
functions of two ciliate TEBPs, TEBPα and TEBPβ. Silencing...

Alternative Titles

Full title

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68664785

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68664785

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb982

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