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MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma

MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68686913

MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma

About this item

Full title

MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2006-07, Vol.313 (5786), p.521-522

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Germline variants in MC1R, the gene encoding the melanocortin-1 receptor, and sun exposure increase risk for melanoma in Caucasians. The majority of melanomas that occur on skin with little evidence of chronic sun-induced damage (non-CSD melanoma) have mutations in the BRAF oncogene, whereas in melanomas on skin with marked CSD (CSD melanoma) these...

Alternative Titles

Full title

MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68686913

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68686913

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1127515

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