MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma
MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Germline variants in MC1R, the gene encoding the melanocortin-1 receptor, and sun exposure increase risk for melanoma in Caucasians. The majority of melanomas that occur on skin with little evidence of chronic sun-induced damage (non-CSD melanoma) have mutations in the BRAF oncogene, whereas in melanomas on skin with marked CSD (CSD melanoma) these...
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Full title
MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma
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TN_cdi_proquest_miscellaneous_68686913
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68686913
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1127515