Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation
Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Immunoglobulin G (IgG) mediates pro- and anti-inflammatory activities through the engagement of its Fc fragment (Fc) with distinct Fcg receptors (FcgRs). One class of Fc-FcgR interactions generates pro-inflammatory effects of immune complexes and cytotoxic antibodies. In contrast, therapeutic intravenous gamma globulin and its Fc fragments are anti...
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Full title
Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation
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TN_cdi_proquest_miscellaneous_68716032
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68716032
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1129594
