The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determine...
The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay
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Publisher
Heidelberg: Springer
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Language
English
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Publisher
Heidelberg: Springer
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Contents
The nonsense-mediated decay (NMD) pathway is an mRNA surveillance mechanism that detects and degrades transcripts containing premature termination codons. The position of a truncating mutation can govern the resulting phenotype as mutations in the last exon evade NMD. In this study we investigated the susceptibility to NMD of six truncating HNF-1be...
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Full title
The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay
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TN_cdi_proquest_miscellaneous_68804701
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68804701
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ISSN
0340-6717
E-ISSN
1432-1203
DOI
10.1007/s00439-005-0023-y
