Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Mutations in the
TSC1
or
TSC2
tumor suppressor genes lead to tuberous sclerosis complex (TSC), a dominant hamartomatous disorder that often presents with mental retardation, epilepsy and autism. The etiology of these neurological symptoms is unclear and the function of the TSC pathway in neurons is unknown. We found that in post-mitotic...
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Full title
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
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TN_cdi_proquest_miscellaneous_68828377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68828377
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1566
