Combining several polymorphisms of thymidylate synthase gene for pharmacogenetic analysis
Combining several polymorphisms of thymidylate synthase gene for pharmacogenetic analysis
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Full title
Author / Creator
Krajinovic, M , Costea, I , Primeau, M , Dulucq, S and Moghrabi, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Thymidylate synthase (TS) is an essential enzyme in proliferating cells and an important target for several chemotherapeutics. Several TS gene polymorphisms correlate with variable TS expression: a double (2R) and triple (3R) 28-bp repeat element, a G to C substitution of the 3R allele and a 6 bp variation in 3′UTR. We have previously shown that ch...
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Full title
Combining several polymorphisms of thymidylate synthase gene for pharmacogenetic analysis
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Record Identifier
TN_cdi_proquest_miscellaneous_68831355
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68831355
Other Identifiers
ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/sj.tpj.6500332
