Regulation of T cell receptor-α gene recombination by transcription
Regulation of T cell receptor-α gene recombination by transcription
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Despite the longstanding correlation between transcription and variable-(diversity)-joining (V(D)J) recombination, it is unknown whether transcription itself can direct recombinase targeting. Here we show that blockade of transcriptional elongation through the mouse T cell receptor-α (
Tcra
) locus suppressed V
α
-to-J
α
recombina...
Alternative Titles
Full title
Regulation of T cell receptor-α gene recombination by transcription
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TN_cdi_proquest_miscellaneous_68874034
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68874034
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni1379
