Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression
Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression
About this item
Full title
Author / Creator
Hu, Yanfen , Ghosh, Sagar , Amleh, Asma , Yue, Wei , Lu, Yunzhe , Katz, Adam and Li, Rong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mutations in
BRCA1
increase risks of familial breast and ovarian cancers, particularly among premenopausal women. While BRCA1 plays an active role in DNA repair, this function alone may not be sufficient to explain why
BRCA1
-associated tumors predominantly occur in estrogen-responsive tissues. Aromatase is the rate-limiting enzyme in e...
Alternative Titles
Full title
Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68901429
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68901429
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1208985
