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X-ray Structure of the EmrE Multidrug Transporter in Complex with a Substrate

X-ray Structure of the EmrE Multidrug Transporter in Complex with a Substrate

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68917926

X-ray Structure of the EmrE Multidrug Transporter in Complex with a Substrate

About this item

Full title

X-ray Structure of the EmrE Multidrug Transporter in Complex with a Substrate

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2005-12, Vol.310 (5756), p.1950-1953

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

EmrE is a prototype of the Small Multidrug Resistance family of efflux transporters and actively expels positively charged hydrophobic drugs across the inner membrane of Escherichia coli. Here, we report the x-ray crystal structure, at 3.7 angstrom resolution, of one conformational state of the EmrE transporter in complex with a translocation subst...

Alternative Titles

Full title

X-ray Structure of the EmrE Multidrug Transporter in Complex with a Substrate

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68917926

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68917926

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1119776

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