Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The engagement of programmed death 1 (PD-1) to its ligands, PD-L1 and PD-L2
1
,
2
,
3
,
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, inhibits proliferation and cytokine production mediated by antibodies to CD3 (refs.
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,
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,
7
). Blocking the PD-1–PD-L1 pathway in mice chronically infected with lymphocytic choriomeningitis virus restores the capac...
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Full title
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
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TN_cdi_proquest_miscellaneous_68926900
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68926900
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1482
