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Identification of Class I MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy

Identification of Class I MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68928585

Identification of Class I MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy

About this item

Full title

Identification of Class I MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (40), p.14889-14894

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Alterations in phosphorylation of cellular proteins are a hallmark of malignant transformation. Degradation of these phosphoproteins could generate cancer-specific class I MHC-associated phosphopeptides recognizable by CD8⁺ T lymphocytes. In a comparative analysis of phosphopeptides presented on the surface of melanoma, ovarian carcinoma, and B lym...

Alternative Titles

Full title

Identification of Class I MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68928585

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68928585

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0604045103

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