AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP
AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP
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Publisher
Boston, MA: Massachusetts Medical Society
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Language
English
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Publisher
Boston, MA: Massachusetts Medical Society
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Scope and Contents
Contents
AMG 531 is a novel dipeptide linked to the Fc fragment of IgG. It is structurally unrelated to thrombopoietin but can stimulate the thrombopoietin receptor. In this phase 1–2 study of AMG 531 in patients with chronic immune thrombocytopenia, there were no major adverse events that could be attributed to the protein. AMG 531 elevated platelet counts...
Alternative Titles
Full title
AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP
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Record Identifier
TN_cdi_proquest_miscellaneous_68963470
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68963470
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa054626
