Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic...
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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It is unclear whether TGF-β, a critical differentiation factor for T cells producing interleukin 17 (T
H
-17 cells), is required for the initiation of experimental autoimmune encephalomyelitis (EAE)
in vivo
. Here we show that mice whose T cells cannot respond to TGF-β signaling lack T
H
-17 cells and do not develop EAE despite th...
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Full title
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
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TN_cdi_proquest_miscellaneous_68977604
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68977604
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni1391
