Generation of in-silico cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A4 inhibition QSAR models
Generation of in-silico cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A4 inhibition QSAR models
About this item
Full title
Author / Creator
Publisher
Netherlands: Springer Nature B.V
Journal title
Language
English
Formats
Publication information
Publisher
Netherlands: Springer Nature B.V
Subjects
More information
Scope and Contents
Contents
In-silico models were generated to predict the extent of inhibition of cytochrome P450 isoenzymes using a set of relatively interpretable descriptors in conjunction with partial least squares (PLS) and regression trees (RT). The former was chosen due to the conservative nature of the resultant models built and the latter to more effectively account...
Alternative Titles
Full title
Generation of in-silico cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A4 inhibition QSAR models
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_69029883
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69029883
Other Identifiers
ISSN
0920-654X
E-ISSN
1573-4951
DOI
10.1007/s10822-007-9139-6
