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Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glio...

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69057405

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

About this item

Full title

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (50), p.20007-20012

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Comprehensive knowledge of the genomic alterations that underlie cancer is a critical foundation for diagnostics, prognostics, and targeted therapeutics. Systematic efforts to analyze cancer genomes are underway, but the analysis is hampered by the lack of a statistical framework to distinguish meaningful events from random background aberrations....

Alternative Titles

Full title

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69057405

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69057405

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0710052104

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