FR177391, A New Anti-hyperlipidemic Agent from Serratia: III. Microbial Conversion of FR177391 and S...
FR177391, A New Anti-hyperlipidemic Agent from Serratia: III. Microbial Conversion of FR177391 and Synthesis of FR177391 Derivatives for Its Target Protein Screening by Chemical Genetic Approaches
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
FR177391 produced by
Serratia liquefaciens
No. 1821 enhances differentiation of mouse 3T3-L1 fibroblasts to adipocytes and reduces the circulating levels of triglyceride in C57BL/KsJ-db/bd mice, an obese non-insulin-dependent diabetes mellitus animal model, although its mechanism of actions remained to be unknown. Its active derivative, 20-hy...
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Full title
FR177391, A New Anti-hyperlipidemic Agent from Serratia: III. Microbial Conversion of FR177391 and Synthesis of FR177391 Derivatives for Its Target Protein Screening by Chemical Genetic Approaches
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TN_cdi_proquest_miscellaneous_69068048
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69068048
Other Identifiers
ISSN
0021-8820
E-ISSN
1881-1469
DOI
10.1038/ja.2005.89
