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Hydrodynamics-and Ultrasound-Based Transfection of Heart with Naked Plasmid DNA

Hydrodynamics-and Ultrasound-Based Transfection of Heart with Naked Plasmid DNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69088471

Hydrodynamics-and Ultrasound-Based Transfection of Heart with Naked Plasmid DNA

About this item

Full title

Hydrodynamics-and Ultrasound-Based Transfection of Heart with Naked Plasmid DNA

Publisher

Larchmont, NY: Liebert

Journal title

Human gene therapy, 2007-12, Vol.18 (12), p.1233-1243

Language

English

Formats

Publication information

Publisher

Larchmont, NY: Liebert

More information

Scope and Contents

Contents

A novel, efficient transfection method, based on ultrasound and hydrodynamics, has been developed to transfect heart tissue with plasmid DNA. An ultrasound probe was aimed at the heart of anesthetized rats for 30 sec, at an intensity of 1 MHz and 2 W/cm2. The aorta was clamped and a phosphate-buffered saline (PBS) solution containing pSV-LacZ was q...

Alternative Titles

Full title

Hydrodynamics-and Ultrasound-Based Transfection of Heart with Naked Plasmid DNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69088471

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69088471

Other Identifiers

ISSN

1043-0342

E-ISSN

1557-7422

DOI

10.1089/hum.2007.063

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